When strangeness threatens to engulf the world, a strange man will come to save it. Sent to investigate a mystery with supernatural overtones, Hellboy discovers the secrets of his own origins, and his link to the Nazi occultists who promised Hitler a final solution in the form of a demonic avatar.

This volume collects issues one through four of the Dark Horse comic-book series, Hellboy : seed of destruction, and stories from San Diego Comic-Con comics #2 and the Comics buyer's guide.