When Meg Murry, joined by her brother Charles Wallace and friend Calvin, embarks on a journey to save her father from an intergalactic source, they come under the guidance of three celestial beings as they travel from one side of the universe to the other.

Mrs. Which -- Meg Murry (age ten) -- The disappearance of Dr. Alex Murry -- Meg Murry (age fourteen) -- Veronica Kiley -- Charles Wallace -- The IT -- Calvin O'Keefe -- Tessering -- Uriel -- The Happy Medium -- Mrs. Which -- Ixchel -- Tessering Well -- Home.