From acclaimed directors/producers Marc Levin and Daphne Pinkerson (HBO's I Am Evidence, Class Divide) comes an enlightening HBO documentary that explores the causes and effects of chronic stress from scientific, economic and sociological perspectives. In investigating the recent three-year decline in U.S. life expectancy for the first time in a hundred years, neurosurgeon and Emmy®-award winning CNN chief medical correspondent Dr. Sanjay Gupta travels across the country, interviewing experts from a wide range of fields who share their insights on why we are experiencing so much stress, its effect on Americans, and its consequences for the health of the nation.

Originally released by Home Box Office, 2019. Streaming video file encoded with permission for digital streaming by Infobase on April 24, 2019.

Drug Overdoses (2:56); --Deaths of Despair (5:06); -- Toxic Stress (3:38); -- Fast-Changing World (3:26); -- "Mortality and Morbidity in the 21st Century" (3:09); -- Is the Economy Improving? (2:25); -- Returning to Michigan (4:02); -- Impact of Job on Health (3:19); -- No Jobs (3:46); -- Suicide (4:29); -- Fixing the Brain (3:21); -- Fundamentally Social Animals (3:15); -- Socio-Economic Status (3:35); -- Reduced Rate of Heart Attacks (4:37); -- Glass' Journey (4:01); -- Social Darwinism (3:00); -- Saving the Human Race (5:02); -- Conclusion: One Nation Under Stress (4:11); -- Credits: One Nation Under Stress (1:20);.