When the Terrigen Mist spread across the world, it triggered the latent genes of regular people and transformed them into Inhumans with amazing powers. As the mysterious Lash takes an unwated interest in the new Inhumans and the newly transformed Flint sees his world fall apart, Queen Medusa finds herself fighting side-by-side with Captain America. When the deposed Inhuman king returns, determined to regain his throne, he quickly takes the royal family captive and conquers Medusa's new island nation. Now, it is up to Flint and his fellow NuHumans to step up and embrace their destiny.

Contains material orginally published in magazine form as Inhuman #1-6.