For many years scientists believed that some kind of internal secretion of the pancreas was the key to preventing diabetes and controlling normal metabolism. No one could find it, until in the summer of 1921 a team at the University of Toronto began trying a new experimental approach suggested by Dr. Frederick Banting. By the spring of 1922, the Toronto researchers — Banting, Charles Best, J.B. Collip and their supervisor, J.J.R. Macleod, were able to announce the discovery of insulin.

From the Historica Canada video collection. Hosted on YouTube.