Indigenous people and salmon have been intertwined for thousands of years in Bristol Bay, Alaska. The knowledge of harvesting, preserving and sharing fish is as important here as any lesson in a book. Today, kids must not only learn from their elders how to fish, but also how to fight. For the last century, corporations have sought to extract the wealth of this rich region. Now Pebble Mine threatens to pollute the pristine headwaters of Bristol Bay. "School of Fish" offers an intimate portrait inside one family's seasonal salmon rituals and their connection to the Bristol Bay Guide Academy, where local youth are empowered through flyfishing to serve as guides and conservationists. Can the next generation step up to defend the most prolific salmon run left on earth?