A new movement, the science of amateurs, is about to transform our daily lives permanently: the "Makers movement". Inspired by Hackers, who are more concerned with software, the makers manipulate molecules, electronics, and materials such as wood or plastic to create open-source hardware. Who are these inspired DIYs? Makers, Biohackers or even Bodyhackers, and hackers are now attacking very real domains. What they have in common is that they are almost all amateurs, yet they could soon be making major discoveries and changing the way we think about science and the world of science and the world.