In 1847, after a confrontation with British soldiers, Jamie Galway awakens from a coma to find his brother, Ryan, and the ancient Irish text they had sworn to protect are missing. Jamie learns that his brother has been forced onto a ship bound for Canada. The ancient script, one of the keys to the secret location of a priceless treasure, has gone with him. On the advice of a secretive band of priests called the Brotherhood, Jamie crosses the Atlantic to find his brother and the lost key.