Yorick Brown and his pet male monkey learn just how valuable they are when they set out across the planet in search of one specific girl in the wake of a strange plague that has killed every man, boy, and mammal with a Y chromosome--except for them.

Statements of responsibility vary in individual vols. "Y : the last man created by Brian K. Vaughan and Pia Guerra." Vol. 1. Originally published in single magazine form as Y: the last man 1-10. Vol. 2. "Originally published in single magazine form as Y: The last man 11-23"--T.p. verso. Vol. 4. Originally published in single magazine form as Y: the last man 37-48. Vol. 5. Originally published in single magazine form as Y: the last man 49-60.