One Night in Mississippi is the story of a young activist named Graden Williams, who was brutally murdered in Mississippi during the sixties. After the perpetrators were charged but quickly released, Graden’s brother, Warren, drifted aimlessly for decades, estranged from the rest of his family and struggling with guilt over his brother’s death. But when the U.S. Justice Department begins re-opening cases like Graden’s more than forty years later, he dedicates himself to bringing Graden’s killers to justice.